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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCC6
All Species:
6.67
Human Site:
S737
Identified Species:
13.33
UniProt:
O95255
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95255
NP_001162.4
1503
164906
S737
A
L
Q
P
D
V
D
S
F
P
E
G
I
H
T
Chimpanzee
Pan troglodytes
XP_001145351
1247
137800
A568
E
L
L
A
R
D
G
A
F
A
E
F
L
R
T
Rhesus Macaque
Macaca mulatta
XP_001109862
1347
147568
G668
V
V
G
P
V
G
A
G
K
S
S
L
L
S
A
Dog
Lupus familis
XP_547113
1504
165780
G738
A
L
W
P
D
V
S
G
F
P
A
G
V
H
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9R1S7
1498
164770
S735
A
L
G
S
D
V
A
S
F
P
A
G
V
H
T
Rat
Rattus norvegicus
O88269
1502
164977
S735
A
L
G
S
D
V
A
S
F
P
A
G
V
H
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517193
1537
172363
I763
A
L
L
P
D
L
E
I
L
P
S
G
D
W
T
Chicken
Gallus gallus
Q5F364
1525
170953
I749
A
L
L
P
D
L
E
I
L
P
M
G
D
R
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001341895
1518
169232
I749
A
L
L
P
D
L
E
I
L
P
G
G
D
T
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91660
1290
143990
I611
P
H
V
D
Q
I
V
I
L
A
N
G
Q
I
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LZJ5
1539
172119
I748
C
L
E
K
D
M
Q
I
M
E
F
G
D
Q
T
Baker's Yeast
Sacchar. cerevisiae
P39109
1515
171103
I737
A
L
T
I
D
L
A
I
L
M
D
G
D
K
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
39.6
84.9
79.5
N.A.
78.5
78.4
N.A.
45
45.3
N.A.
45.9
N.A.
28.2
N.A.
N.A.
N.A.
Protein Similarity:
100
55.6
86.8
87.3
N.A.
85.8
86
N.A.
63.5
63.2
N.A.
64.1
N.A.
46.9
N.A.
N.A.
N.A.
P-Site Identity:
100
26.6
6.6
66.6
N.A.
66.6
66.6
N.A.
46.6
46.6
N.A.
46.6
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
40
20
73.3
N.A.
73.3
73.3
N.A.
60
60
N.A.
60
N.A.
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.9
33.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
49.5
52.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
67
0
0
9
0
0
34
9
0
17
25
0
0
0
9
% A
% Cys:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
9
75
9
9
0
0
0
9
0
42
0
0
% D
% Glu:
9
0
9
0
0
0
25
0
0
9
17
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
42
0
9
9
0
0
0
% F
% Gly:
0
0
25
0
0
9
9
17
0
0
9
84
0
0
0
% G
% His:
0
9
0
0
0
0
0
0
0
0
0
0
0
34
0
% H
% Ile:
0
0
0
9
0
9
0
50
0
0
0
0
9
9
0
% I
% Lys:
0
0
0
9
0
0
0
0
9
0
0
0
0
9
9
% K
% Leu:
0
84
34
0
0
34
0
0
42
0
0
9
17
0
0
% L
% Met:
0
0
0
0
0
9
0
0
9
9
9
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% N
% Pro:
9
0
0
50
0
0
0
0
0
59
0
0
0
0
0
% P
% Gln:
0
0
9
0
9
0
9
0
0
0
0
0
9
9
0
% Q
% Arg:
0
0
0
0
9
0
0
0
0
0
0
0
0
17
0
% R
% Ser:
0
0
0
17
0
0
9
25
0
9
17
0
0
9
0
% S
% Thr:
0
0
9
0
0
0
0
0
0
0
0
0
0
9
84
% T
% Val:
9
9
9
0
9
34
9
0
0
0
0
0
25
0
0
% V
% Trp:
0
0
9
0
0
0
0
0
0
0
0
0
0
9
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _